Node.js adaptability in a medium to large, regulated enterprise can be quite challenging; various process items including risk & compliance, OSS, supportability, static-code analysis, IDE/SC integration info-sec concerns etc need to be addressed before any new technology can be adapted.
My co-worker Daniel Imrie-Situnayake did a great presentation on this very topic titled "Within the Whale: a story of enterprise Node advocacy from the inside out".
